ToxTime: Ethyl Glucuronide (EtG) in Hair and Nail – A review and Recent Updates

Please join us for ToxTime with Joseph Jones, Ph.D., NRCC-TC, Chief Operating Officer at USDTL, as he presents on what is new with using hair and nail to detect Ethyl Glucuronide (EtG), a long-term ethanol biomarker. 

What You’ll Learn

• What is Ethyl Glucuronide (EtG)
• Ethyl Glucuronide (EtG) testing in
  • Urine
  • Hair
  • Nail
  • Umbilical Cord Tissue
• A brief overview of previous studies
• And more…

Click Here to Watch the Webinar

When drugs are swallowed, they may be broken down (metabolized) by enzymes and/or absorbed using transporters in cells found in the small intestine. Grapefruit juice can cause problems with these enzymes and transporters, causing too much or too little drug in the body.

Some drugs, like statins used to lower cholesterol, are broken down by enzymes. Grapefruit juice can block the action of these enzymes, increasing the amount of drug in the body and may cause more side effects.

Photo from the U.S. Food & Drug Administration

Other drugs, like Allegra (fexofenadine) used to treat allergies, are moved by transporters into the body’s cells. Grapefruit juice can block the action of transporters, decreasing the amount of drug in the body and may cause the drug to not work as well.

Photo from the U.S. Food & Drug Administration

Grapefruits: Food and Drug Interaction

The Canadian Medical Association Journal (CMAJ) released a review of drugs that interact with Grapefruit, “43 drugs in dangerous ways.”

List of medications that may cause severe side-effects when interacting with grapefruit.

Image by CBC Radio Canada, Information from the Canadian Medical Association Journal

Information collected from:

• https://www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-drugs-dont-mix 
• https://www.cmaj.ca/content/185/4/309
• https://www.cbc.ca/news/health/grapefruit-juice-interaction-with-drugs-can-be-deadly-1.1253489