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Child Hair Announcements

Report Change Notification Report Change Notification

18-Apr-2016

Effective July 18, 2016, USDTL will be implementing a new way of reporting quantitative results. In order to satisfy accreditation requirement, the concentrations of drugs exceeding the Upper Limit of Quantification (ULOQ) for any given drug will be reported as > ULOQ (greater than ULOQ). The ULOQ will be provided.

Quantity Not Sufficient (QNS) Explained Quantity Not Sufficient (QNS) Explained

02-Mar-2016

Quantity Not Sufficient (QNS) is a result of not having a sufficient quantity (volume) of
specimen to test for the panels ordered. The amount of specimen required for collection
is directly related to the amount of specimen needed to screen and confirm for the panels we offer. The initial screening uses a portion of the original specimen and the confirmation testing uses another portion of the original specimen. To forensically confirm positives, means running a new test, with a new portion of the original specimen, using a different analytical technique.

Updated Policy Regarding Insufficient Specimen Volumes Updated Collection Instructions Updated Policy Regarding Insufficient Specimen Volumes Updated Collection Instructions

1-Apr-2015

It is our first priority to deliver testing results that provide the most valuable information possible for your substance abuse testing needs. To better accomplish this duty to our clients, we are updating our policy concerning specimens that do not have sufficient volume for both preliminary testing and confirmation. Effective April 1, 2015, confirmatory tests that cannot be completed due to insufficient specimen volume will be canceled on an individual drug class and/or analyte basis. We will report confirmation results for each test for which there is sufficient volume of specimen available, giving you access to more information.

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Child Hair FAQs

*Click the green and white plus sign beside each question to view the answer.

Can a hair test be manipulated by the donor?

Yes. Bleaching, perming, dyeing and straightening can affect the outcome of a hair test. Cosmetically treated hair should not be collected.

Can a hair test be used to prove that a previously taken urine test was inaccurate?

No. The results of any second collected specimen have absolutely no bearing on the validity of the results of the first collected specimen. Furthermore, each matrix has its own advantages, disadvantages and limits of interpretation.

Can a hair test determine how much or how often someone is using a drug?

No. Hair is a reservoir matrix, where drugs can collect and/or degrade over time. When testing any reservoir matrix, you are unable to back-track and determine time, dosage or frequency because there are simply too many variables involved.

Can someone test positive in hair because of passive or environmental exposure?

Yes, drugs are incorporated into hair by three major routes: environmental exposure, sweat and sebum from the scalp and blood flow through the follicle. Environmental exposure however will only generate a positive for the parent drug. Example: methamphetamine only. The other two mechanisms lay down drug and drug metabolites. Example: amphetamine/methamphetamine positive.

Does race make a difference in hair testing results?

Hair color, not race, is one of the most important variables in determining the quantity of drug found in the hair. Dark hair binds drug tighter than light hair.

How long can drugs be detected in body hair?

Body hair has a different growth cycle compared to head hair. Body hair may go dormant and remain in place up to one year. A positive result reflects exposure up to 12 months.

How long can drugs be detected in head hair?

Once a drug is incorporated into hair, it begins to slowly leach out due to normal daily hygiene and exposure to the elements. Most drugs have disappeared by three months. Furthermore, the laboratory only analyzes the first 1.5 inches (3.9 centimeters) nearest the scalp. Hair grows at an average rate of 0.5 inches per month.

If the quantity of drug or alcohol metabolite detected is high, could that be an indication that the donor (1) was consuming a large amount, (2) was using recently, or (3) was using frequently?

There are too many variables for anyone to know time of use, dosage, or frequency from the result(s) of a drug test. Reservoir matrices such as hair, fingernail, umbilical cord, and meconium continuously collect drug and alcohol biomarkers. This makes it difficult to determine specific details of use. Because the biomarker is collected over a period of time, the results represent total accumulation that cannot be pin-pointed to specific times/dates/dosages, etc.

Q: Why are both ethyl sulfate (EtS) and ethyl glucuronide (EtG) included in urine testing for alcohol use, but only EtG in fingernail or hair testing?

A: For urine testing, it is standard practice in the field of toxicology to include both EtS and EtG, because EtG is subject to bacterial production and degradation if a urine sample is contaminated (e.g. when the donor has a urinary tract infection). EtS is not subject to bacterial production or degradation, and provides a second, more reliable alcohol biomarker in these urine contamination scenarios. Other specimens types, such as fingernails and hair, do not have this issue, so only EtG is measured in those sample types.

What does a positive hair test result mean?

The only interpretation that can come from a positive hair test is that the individual used or was exposed to drug during the three months prior to collection.

Why do we test for EtG in hair and not FAEE?

FAEE is less sensitive and can produce false positives. Hairspray and other hair products can produce FAEEs in hair. There is no enzyme in our hair that can create ETG from those products.

Why was one matrix positive and another negative on the same donor?

There are several explanations for this. 

  1. Different sample matrices have different detection time frames. The result of any second collected specimen has no bearing on the validity of a first collected specimen. For example, a hair sample with a three month window of detection might test positive for a particular substance, while a urine sample from the same donor, with a 2-3 day window of detection, might test negative. In this case, the donor has used that substance within the past three months, but may not have used it within the most recent three days.
  2. The result of any second collected specimen has no bearing on the validity of a first collected specimen. Therefore, a negative result observed for the umbilical cord does not refute a positive result observed on the maternal urine specimen and the reverse is true as well. There are many legitimate reasons for discrepant urine and umbilical cord results. 
  3. The urine specimen was a screen only result and was not confirmed using an appropriate mass spectrometric method. The screen only urine result is a clinically valid result, however, without an appropriate mass spectrometric confirmation, the urine result has no value in a forensic proceeding. 
  4. Lastly, some placentas can prevent some compounds from reaching the fetus. There are documented cases of maternal ingestion without in utero exposure.

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