Grants

 

USDTL has a strong history of research and innovation in analytical toxicology. Our New Applications Department does more research than other laboratories 10 times our size. We are one of the few private laboratories to be funded by Small Business Innovation Research (SBIR) grants, having secured over $2 million in funding to date. Currently, USDTL has an active SBIR grant from the National Institute on Alcohol Abuse and Alcoholism:

 

Hair ethyl glucuronide (EtG) as a long-term alcohol biomarker

  • determining the dynamics of EtG in hair and fingernails by studying its dose response to alcohol uptake in alcohol-consuming college students; measuring the half-time of its washout rate from hair and fingernails in a population of volunteers undergoing residential treatment in an alcohol abuse recovery program. The data obtained from this study will establish hair EtG’s utility as a long-term alcohol biomarker.

Grant 2 R44 AA016463-02

 

Completed research grants include:

 

National Institute of Drug Abuse (2004-2008)

Diagnostic viability of umbilical cord specimens

  • feasibility of using umbilical cord to diagnose neonatal drug exposure

Grant 1 R43 DA017412-01

 

Diagnostic viability of umbilical cord specimens

  • developing and commercializing umbilical cord drug of abuse assays

Grant 2 R44 DA017412-02

 

National Institute on Alcohol Abuse and Alcoholism (1997-2010)

Fetal alcohol exposure: commercial assay development SBIR Phase 1

  • fatty acid ethyl esters (FAEE) in meconium as fetal alcohol exposure assay

Grant 1 R43 AA11483-01

 

Using human hair to determine long-term alcohol abuse

  • using FAEE in hair to determine alcohol abuse

Grant 1 R43 AA014768-01

 

Hair ethyl glucuronide (EtG) as a long-term alcohol biomarker

  • hair EtG superior to hair FAEE as a long-term alcohol biomarker

Grant 1 R43 AA016463-01

 

Phosphatidylethanol as an alcohol biomarker in umbilical cord tissue

  • using phosphotidylethanol as an alcohol biomarker in umbilical cord

Grant 1 R43 AA016702-01

 

Phosphatidylethanol as an alcohol biomarker in neonatal blood spots

  • feasibility of a screening assay for alcohol-exposed neonates

Grant 1 R43 AA017792-01

 

Hair EtG as a long-term alcohol biomarker

  • determining relationship between alcohol dose and amount of biomarker in hair and nails
  • determining half-time of EtG loss in hair and nails

Grant 1 R43 AA016463-01